Abstract #3486

Alteration of IVIM Parameters by Signal Variation of Multiple b-value DWI Measurement

Chun-Jung Juan¹, Teng-Chieh Cheng², Tzu-Cheng Chao³, Teng-Yi Huang⁴, Chia-Wei Lin¹, Wu-Chung Shen¹, and Yi-Jui Liu²

¹Department of Medical Imaging, China Medical University Hsinchu Hospital, Hsinchu, Taiwan, taichung, Taiwan, ²Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, taichung, Taiwan, ³Department of Computer Science and Information Engineering, National Cheng-Kung University, Tainan, Taiwan., tainan, Taiwan, ⁴Department of Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan, taipei, Taiwan

The purpose of this study is to explore the alterations of IVIM measurement among multiple b-value sets with different low b-value and high b-value numbers using EPDWI. EPDWI with 41 different b-values was performed. For simulating the situation in clinic, five sets of 16 b-value numbers were chose from the 41 b values. DWI data of 1000 pixels for each WM, GM and CSF were randomly chose to evaluate the error of IVIM parameters. Our study demonstrated the variation of DWI signal with multi-b-value, affect the evaluation of Df and f but does not affect Ds in pixel-wise IVIM analysis.

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