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Abstract #3530

Golden-Angle Rotating Single-Shot Acquisition (GA-RoSA) for Simultaneous High-Resolution DTI and IVIM

Qiuting Wen1, Feng Li2, Kun Zhou3, Christianne Leidecker4, and Yu-Chien Wu1

1Indiana University, School of Medicine, Indianapolis, IN, United States, 2Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY, United States, 3Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, 4Siemens Medical Solutions, Inc., Chicago, IL, United States

High-resolution DWI often relies on multi-shot acquisitions, which suffer from long acquisition time and motion-related phase variations. Although effort has been made to accelerate DWI acquisitions, acquiring b=0 images still requires multiple shots and multiple averages. In this work, in addition to accelerating DWI acquisitions, the proposed method (GA-RoSA) further rearranged the b=0 acquisitions to cover a range of lower b-values without increasing scan times, so that IVIM parameters can be obtained for free. With a golden-angle rotation scheme, GA-RoSA introduced sampling incoherence facilitating its combination with sparsity-based reconstruction approaches. We demonstrated its feasibility for simultaneous high-resolution DTI and IVIM.

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