Abstract #3577

Powering Up Microstructural Imaging: assessing cross-metric and cross-tract statistical power on an ultra-strong gradient MRI system

Kristin Koller¹, Suryanarayana Umesh Rudapandra¹, Maxime Chamberland¹, Erika Raven¹, Greg D Parker¹, Chantal Tax¹, Mark Drakesmith¹, John C Evans¹, Tobias C Wood², and Derek K Jones¹

¹Cardiff University Brain Research Imaging Centre, Cardiff University, Cardiff, United Kingdom, ²Department of Neuroimaging, King's College London, London, United Kingdom

We present cross-metric and cross-tract assessment of test-retest repeatability for microstructure measures on an ultra strong gradient MRI scanner (CONNECTOM 3T) in the human brain. We show that several MRI metrics of tissue microstructure are reliable and present relative sample sizes required to provide sufficient statistical power across different white matter pathways and microstructure metrics.

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