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Abstract #3622

Assessing inter-vender reproducibility of diffusion tensor imaging of the spinal cord for multi-center imaging studies

Mitsuhiro Kitamura1, Satoshi Maki1, Takeo Furuya1, Takuya Miyamoto1, Yasuhiro Shiga1, Kazuhide Inage1, Sumihisa Orita1, Koji Matsumoto2, Shingo Terakado3, Yoshitada Masuda2, and Seiji Ohtori1

1Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba City, Japan, 2radiology, Chiba University Hospital, Chiba City, Japan, 3radiology, Asahi General Hospital, Asahi City, Japan

In this study, we assessed the inter-vendor precision of diffusion tensor imaging (DTI) metrics using consensus acquisition protocol across 3T scanners from 3 main vendor at the two sites. The data were acquired from the traveling human healthy volunteer. DTI data and anatomical images were also acquired and imaging data were processed using the Spinal Cord Toolbox (SCT). Relatively higher inter vender reproducibility of fractional anisotropy (FA) in and cross-sectional area were demonstrated and it is considered feasible to conduct multicenter DTI studies of the spinal cord using FA value as biomarker and SCT as postprocessing tool.

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