Abstract #3646

Kärger Model Difficulties for In Vivo DWI

Catherine L Lian^1,2, Brendan Moloney², Eric M Baker², Greg Wilson³, Erin W Gilbert⁴, Thomas M Barbara², Charles S Springer², and Xin Li²

¹Westview High School, Portland, OR, United States, ²Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR, United States, ³Home, Mill Creek, WA, United States, ⁴Surgery, Oregon Health & Science University, Portland, OR, United States

Although it is well known that diffusion-weighted imaging (DWI) is sensitive to in vivo trans-membrane water-exchange, quantitative interpretation of the diffusion b-space decay remains difficult. Using random-walk simulated DWI data, this study investigates the feasibility and reliability in studying the water exchange effects with a multi-exponential fitting approach on DWI data.

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