Abstract #3663

Functional stability of clinical research neurological scanners

Antonio Napolitano¹, Martina Lucignani¹, Francesca Bottino¹, Anna Nigri², Domenico Aquino², Fulvia Palesi³, Maria Grazia Bruzzone², Michela Tosetti^4,5, Claudia A. M. Gandini Wheeler-Kingshott^6,7,8, and the Italian IRCCS advanced neuroimaging network⁹

¹Medical Physics Department, Bambino Gesù Children's Hospital, Rome, Italy, ²Neuroradiology Department, Carlo Besta Neurological Institute, Milan, Italy, ³Brain MRI 3T Center, Mondino National Neurological Institute, Pavia, Italy, ⁴IRCCS Stella Maris Foundation, Pisa, Italy, ⁵Imago7 Foundation, Pisa, Italy, ⁶Brain MRI 3T Research Center, Mondino National Neurological Institute, Pavia, Italy, ⁷Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy, ⁸Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, United Kingdom, ⁹Advanced Neuroimaging Network of Italian Research Neurological Institutes (IRCCS), Italy, Italy

A multicenter network of Italian Neurological Research Hospital was recently started. Its first aim was to establish quality assessment protocols for future quantitative imaging studies. In this context, we report the outcome of the first 6 months of data collection using a dedicated phantom and processing pipeline. Scanner performance was assessed in terms of several stability indicators, grouped by manufacturer. The preliminary results represent the initial step towards a large-scale scanner stability assessment in clinical settings. We expected to gather regular data from all the sites in order to broaden data analysis and assess the multi-site temporal stability.

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