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Abstract #3663

Functional stability of clinical research neurological scanners

Antonio Napolitano1, Martina Lucignani1, Francesca Bottino1, Anna Nigri2, Domenico Aquino2, Fulvia Palesi3, Maria Grazia Bruzzone2, Michela Tosetti4,5, Claudia A. M. Gandini Wheeler-Kingshott6,7,8, and the Italian IRCCS advanced neuroimaging network9

1Medical Physics Department, Bambino Gesù Children's Hospital, Rome, Italy, 2Neuroradiology Department, Carlo Besta Neurological Institute, Milan, Italy, 3Brain MRI 3T Center, Mondino National Neurological Institute, Pavia, Italy, 4IRCCS Stella Maris Foundation, Pisa, Italy, 5Imago7 Foundation, Pisa, Italy, 6Brain MRI 3T Research Center, Mondino National Neurological Institute, Pavia, Italy, 7Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy, 8Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, United Kingdom, 9Advanced Neuroimaging Network of Italian Research Neurological Institutes (IRCCS), Italy, Italy

A multicenter network of Italian Neurological Research Hospital was recently started. Its first aim was to establish quality assessment protocols for future quantitative imaging studies. In this context, we report the outcome of the first 6 months of data collection using a dedicated phantom and processing pipeline. Scanner performance was assessed in terms of several stability indicators, grouped by manufacturer. The preliminary results represent the initial step towards a large-scale scanner stability assessment in clinical settings. We expected to gather regular data from all the sites in order to broaden data analysis and assess the multi-site temporal stability.

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