Abstract #3671

The changes of R2’ in quantitative evaluation of acute renal injury: Preliminary animal study

Weizheng Gao¹, Chengyan Wang², Hanjing Kong¹, Min Yang³, Xiaodong Zhang³, Jue Zhang¹, and Xiaoying Wang³

¹Peking University, Beijing, China, ²Shanghai Jiao Tong University, Shanghai, China, ³Peking University First Hospital, Beijing, China

As a recently proposed novel pulse sequence, the pulse-shifting multi-echo asymmetric spin echo (psMASE) can isolate R2’ in real time. Combined with gas challenge, it can be used to evaluate acute renal injury (AKI) quantitatively. In this study, we further investigated the feasibility of the change of R2' value (dR2’) in distinguishing different severities of AKI using this sequence. Results suggested that there was significant difference between the different severities of AKI and dR2’, which indicating that the dR2' value can serve as a potential quantitative indicator for acute renal injury evaluation.

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