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Abstract #3774

Influence of multiband factor on temporal SNR limits using a clinical BOLD-EPI sequence

Pim Pullens1,2, Jasper Degryse3, Han Bossier3, Bieke Moerkerke3, Marcel Brass4, Guy Vingerhoets4, and Rik Achten2

1Department of Radiology, Ghent University Hospital, Gent, Belgium, 2Department of Diagnostic Sciences, Ghent University, Ghent, Belgium, 3Department of Data Analysis, Ghent University, Ghent, Belgium, 4Department of Experimental Psychology, Ghent University, Ghent, Belgium

Detectability of BOLD signal change is determined by temporal SNR (tSNR, mean divided by standard deviation of the signal over time), and ultimately determines how long needs to be scanned to obtain significant results in a fMRI experiment. With the clinical availability of multiband BOLD-EPI, TR can be shortened significantly, but it is unclear how MB factor influences tSNR. We show in a human subject that tSNR limits up to 192 can be reached and that multiple combinations of MB factor and voxel size can be used to reach similar tSNR values.

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