Abstract #3774

Influence of multiband factor on temporal SNR limits using a clinical BOLD-EPI sequence

Pim Pullens^1,2, Jasper Degryse³, Han Bossier³, Bieke Moerkerke³, Marcel Brass⁴, Guy Vingerhoets⁴, and Rik Achten²

¹Department of Radiology, Ghent University Hospital, Gent, Belgium, ²Department of Diagnostic Sciences, Ghent University, Ghent, Belgium, ³Department of Data Analysis, Ghent University, Ghent, Belgium, ⁴Department of Experimental Psychology, Ghent University, Ghent, Belgium

Detectability of BOLD signal change is determined by temporal SNR (tSNR, mean divided by standard deviation of the signal over time), and ultimately determines how long needs to be scanned to obtain significant results in a fMRI experiment. With the clinical availability of multiband BOLD-EPI, TR can be shortened significantly, but it is unclear how MB factor influences tSNR. We show in a human subject that tSNR limits up to 192 can be reached and that multiple combinations of MB factor and voxel size can be used to reach similar tSNR values.

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