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Abstract #3785

Dual-route mechanism for pictorial visual perception in developmental dyslexia

Sunita Gudwani1, S.Senthil Kumaran1, Rajesh Sagar2, Madhuri Behari3, Manju Mehta4, Vaishna Narang5, SN Dwivedi6, and NR Jagannathan1

1Department of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India, 2Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India, 3Department of Neurology, Fortis Hospital, New Delhi, India, 4Department of Psychiatry (Psychology Unit), All India Institute of Medical Sciences, New Delhi, India, 5Department of Linguistics, School of Language, Jawahar Lal Nehru University, New Delhi, India, 6Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India

Reading a window to world’s information, is a coordinated skill of grapheme-phoneme interface (letter-sound) at symbolic level. Inefficient mapping of this alphabets-horizontal string is labeled as dyslexia (reading problem). It can be developmental or acquired (post-stroke) disorder. Developmental dyslexia (DD) is heterogeneous state with disputed underlying mechanism(s) constraining optimal remediation. Compared to typical readers, DD literature is bifurcated into children with strength and impairment for visual perception. To unfold it neurobiologically, nonsymbolic visual processing role was studied. Observed bilateral brain activation (functional MRI) of ventral stream (inferior occipital and fusiform) and modified dorsal route-gating for figure-ground filtering in DD.

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