Abstract #3788

Effect of cue induced craving on brain morphometry and function in adolescent inhalant users

Shobhit Jain¹, S Senthil Kumaran², Anju Dhawan¹, Raman Deep Pattanayak ¹, and Raka Jain³

¹Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India, ²Department of NMR & MRI Facility, All India Institute of Medical Sciences, New Delhi, India, ³National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi, India

Inhalants are legal, inexpensive substances that are often abused by adolescents. This study compared the BOLD changes in brain associated with cue-induced craving in adolescent inhalant users (n=13) and healthy controls (n=12) to elucidate the neural mechanisms associated with cue-induced craving. The cases exhibited an increased activation of superior occipital gyrus, inferior parietal lobule, cingulate gyrus, thalamus, and culmen and a decreased activation of insula as compared to control group for craving cues. Visual cue reactivity was associated with activation of the areas responsible for visual perception, visuo-spatial attention and working memory, control and motivation.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.