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Abstract #3802

Disrupted functional connectivity strength in overactive bladder syndrome patients

Long Zuo1, Shuangkun Wang1, Yang Zhou1, Hua Gu1, Biao Wang1, and Tao Jiang1

1Beijing Chaoyang Hospital, Beijing, China

A dysregulation of the brain-bladder control network has been revealed by the functional brain imaging studies. However, the brain functional connectivity strength (FCS) of OAB still remains unclear. Our study investigated the changes of intrinsic whole brain functional connectivity pattern in OAB using FCS. Patients with OAB have impaired pattern of FCS, which shows abnormal short-range and long-range FCS in brain regions associated with brain-bladder network. Behavioural treatments of the OAB based on fMRI may provide new sight into clinical practice.

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