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Abstract #3805

Zero TE based screening for transcranial MR guided focused ultrasound

Jaime Caballero1, Rafael Rodríguez-Rojas1, Raul Martínez-Fernández1, Marta Del-Alamo1, Pablo Garcia-Polo2, and Jose A. Pineda-Pardo3

1hmCINAC, University Hospital HM Puerta del Sur, Móstoles, Spain, 2GE Healthcare, Madrid, Spain, 3Neuroimaging, hmCINAC, Móstoles, Spain

The high acoustic impedance of the skull limits the performance of tissue ablation applications with tcMRgFUS. Skull characterization is currently based on CT. Zero echo time (ZTE) images could represent a safer alternative in this matter. CT and ZTE images were acquired in sixteen essential tremor patients that underwent tcMRgFUS. Several skull measures were obtained for both images. ZTE and CT based metrics were strongly correlated. Furthermore skull thickness and the skull density ratio were able to predict the efficiency of the treatment. In conclusion, ZTE based measures are able to determine the suitability of a tcMRgFUS candidate.

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