A total of 273 patients who received needle localization with a bare-hand technique for suspicious breast lesions by using 1.5 T MR-guided were included in our study. The puncture method was similar to CT-guided needle localization of lung nodule. The success rate of localization was 100% (273/273). Procedure time of all the cases ranged from 5 to 30 min (mean, 14.3 min). Our MRI-guided bare-hand needle localization of suspicious breast lesions is a handy, safe, rapid, and accurate interventional method. The lesions that are located at axillary region of breast，areola area, and the special area near the chest wall can all be precisely localized.