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Abstract #3840

Catheter-based Arterial Input Function for Quantitative Perfusion Measurements with Intra-arterial Injection

Simon Stephan1, Simon Reiss1, Thomas Lottner1, Ali Caglar Özen1, and Michael Bock1

1Dept. of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

MR-guided vascular interventions allow for direct injection of contrast agent (CA) through a catheter, which can be used for perfusion measurements of the target tissue, for example, the myocardium in MR-guided coronary catheterizations. For a quantitative perfusion measurement an arterial input function (AIF) is required that describes the CA concentration-time curve in the artery. In this work we show initial results of two methods to determine the AIF during an intervention and demonstrate the feasibility of measuring the AIF in intra-arterial CA injections based on the signal of an active guiding catheter.

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