Abstract #3897

Peculiarities of brain activation during dominant hand tactile perception in lateralized Parkinson disease

Oleksii Omelchenko¹

¹Anatomy and Physiology, Taras Shevchenko National University of Kyiv, Kyiv, Ukraine

Parkinson's disease (PD) in mostly presented with asymmetrical motor symptoms. Disturbed sensorimotor integration and decrease of somatosensory cortex activation was previously shown. We analyzed brain activation and connectivity during the unilateral tactile stimulation in primary and non-primary hand lateralized PD patients. We have demonstrated steady contralateral S1 activation in PD. Primary hand tactile stimulation in primary hand lateralized PD patients evokes activation of primary and associative sensory, motor and executive nodes of the cortex. Mirror neuron system was activated in primary hand stimulation in PD patients. Tactile stimuli processing evokes increased connectivity of globus pallidus, premotor, prefrontal and parietal cortex.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.