To study amygdala function, we used multi-echo EPI sequence as fMRI at 7T to reduce the effects of local magnetic field inhomogeneity in the region. Additionally, to increase sensitivity, we modified a hemodynamic response function model from an empirical model. These methods allowed us to detect robust activation of the amygdala and brain areas related to emotional face discrimination tasks in addition to increased functional connectivity between them. Using an appropriate acquisition method and statistical model can improve sensitivity in regions whose signal is suffered by local magnetic field inhomogeneity in ultra-high field fMRI studies.
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