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Abstract #3918

Which lateralization index and which language task should we use in lateralization test?

Kayako Matsuo1, Kazufumi Akiyama1, and Yasushi Kaji2

1Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University, Tochigi, Japan, 2Department of Radiology, Dokkyo Medical University, Tochigi, Japan

It is crucial to select a good language task in fMRI to examine the language lateralization. We examined the concordances of 6 lateralization indices (LIs) using 4 language tasks. We confirmed that our previously developed LI, AveLI, showed a better concordance of index values across 4 tasks. Also, the verb generation task showed a better concordance across the 6 LIs than other tasks. In addition, this task showed a plausible ratio of rightward asymmetry (5 out of 16 left/both-hand preferred). Thus, we concluded to conduct the verb generation task and compute AveLI as a robust index of the language lateralization.

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