At high magnetic field, 7T and above, T2-weighted fMRI has drawn attention for its high specificity in columnar and layer specific fMRI by minimizing draining vein effects compared to T2*-weighted GE-EPI based fMRI. 3D inner-volume gradient and spin echo (3D-GRASE) has been proposed and used for sub-millimeter resolution. However, reduced field-of-view (FOV) imaging in general has disadvantages compared to GE-EPI: 1) small FOV, 2) T2 induced blurring, both along the partition direction, and 3) low signal-to-noise ratio (SNR) from long TE with EPI readouts. To address both issues, 3D GRASE is extended to volumetric ky-kz random undersampling followed by performing CS for signal recovery (3D CS-GRASE). The ky-kz undersampling extends volume coverage without compromising the blurring while enhancing SNR due to short TE from inplane undersampling.
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