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Abstract #3944

Silent fMRI with visual and auditory stimulation using 3D radial T2*-weighted ZTE-BURST sequence

Marta Lancione1,2, Guido Buonincontri2,3, Luca Cecchetti1, Mauro Costagli2,3, Jan W Kurzawski2,4, Emiliano Ricciardi1, Rolf F Schulte5, Ana Beatriz Solana Sanchez5, and Michela Tosetti2,3

1IMT School for Advanced Studies, Lucca, Italy, 2IMAGO7 Foundation, Pisa, Italy, 3IRCCS Stella Maris, Pisa, Italy, 4Italian National Institute of Nuclear Physics, Pisa, Italy, 5GE Healthcare, Munich, Germany

Besides being a major cause of patient discomfort, acoustic scanner noise (ASN) represents one of the main confounding factors in fMRI with auditory stimulation and in resting state conditions. The recent development of silent T2*-weighted MR sequences may open up new possibilities in the study of brain function in a quieter environment offering novel tools of acquisition, alternative to EPI. In this feasibility study we aim to produce and evaluate BOLD activity maps at 7T using a novel 3D radial T2* sequence (ZTE-BURST).

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