Abstract #3944

Silent fMRI with visual and auditory stimulation using 3D radial T2*-weighted ZTE-BURST sequence

Marta Lancione^1,2, Guido Buonincontri^2,3, Luca Cecchetti¹, Mauro Costagli^2,3, Jan W Kurzawski^2,4, Emiliano Ricciardi¹, Rolf F Schulte⁵, Ana Beatriz Solana Sanchez⁵, and Michela Tosetti^2,3

¹IMT School for Advanced Studies, Lucca, Italy, ²IMAGO7 Foundation, Pisa, Italy, ³IRCCS Stella Maris, Pisa, Italy, ⁴Italian National Institute of Nuclear Physics, Pisa, Italy, ⁵GE Healthcare, Munich, Germany

Besides being a major cause of patient discomfort, acoustic scanner noise (ASN) represents one of the main confounding factors in fMRI with auditory stimulation and in resting state conditions. The recent development of silent T2*-weighted MR sequences may open up new possibilities in the study of brain function in a quieter environment offering novel tools of acquisition, alternative to EPI. In this feasibility study we aim to produce and evaluate BOLD activity maps at 7T using a novel 3D radial T2* sequence (ZTE-BURST).

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