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Abstract #4006

Fat quantification using simultaneous, separate water and fat excitation combined with CAIPIRINHA

Beáta Bachratá1,2, Radim Kořínek3, Bernhard Strasser1,4, Albrecht Ingo Schmid5, Martin Krššák2,6, Wolfgang Bogner1, Siegfried Trattnig1,2, and Simon Daniel Robinson1

1Department of Biomedical Imaging and Image-Guided Therapy, High Field MR Centre, Medical University of Vienna, Vienna, Austria, 2Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, 3Institute of Scientific Instruments of the CAS, Brno, Czech Republic, 4Department of Radiology, Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States, 5Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria, 6Department of Internal Medicine III, Division of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria

Fat quantification by MRI plays an important role in assessing hepatic steatosis and bone marrow changes. We propose a new method for fat quantification in which multiband pulses are used to separately but simultaneously excite fat and water. CAIPIRINHA encoding allows overlapping images of the two species to be separated. Fat fraction maps can be calculated from fat and water images with appropriate consideration of relaxation times. The proposed method is validated on phantoms with different fat concentrations, where it yields similar fat fraction values to the Dixon approach and single-voxel spectroscopy.

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