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Abstract #4008

Separation of Water and Fat during Spin-Lock Magnetic Resonance Imaging with Multifrequency Fat Spectrum Modeling

Weitian Chen1, Baiyan Jiang1, Maximilian N. Diefenbach2, Dong Liang3, and Dimitrios C. Karampinos2

1Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Shatin, Hong Kong, 2Department of Diagnostic and Interventional Radiology, Technical University of Munich, Munich, Germany, 3Shenzhen Institutes of Advanced Technology, Shenzhen, China

Spin-lock technologies are useful for probing macromolecular environment of tissue. The conventional spin-lock approaches cannot lock water and fat spins simultaneously due to chemical shift effect of fat, which can lead to artifacts in tissues with fatty infiltration. Based on the latest development of the spin-lock technique, we propose spin-lock Dixon methods to perform water-fat separation in spin-lock MRI. Our methods may offer a solution to perform reliable spin-lock MRI in tissues with fatty infiltration.

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