Abstract #4081

Real-Time Imaging during Free Breathing for Patient-Friendly V/Q Scan of the Whole Lung in One Minute at 3T

Andreas Voskrebenzev^1,2, Till Kaireit^1,2, Marcel Gutberlet^1,2, Filip Klimes^1,2, Lea Behrendt^1,2, Christoph Forman³, Frank Wacker^1,2, and Jens Vogel-Claussen^1,2

¹Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany, ²Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany, ³Magnetic Resonance, Siemens Healthcare GmbH, Erlangen, Germany

MRI techniques like phase-resolved functional lung imaging (PREFUL) offer the possibility for pulmonary ventilation (V) / perfusion (Q) imaging without ionizing radiation or contrast agents. One major drawback of such methods is the long acquisition time, if a whole lung coverage is required. In this study, five healthy volunteers were scanned with a highly accelerated 2D multi-slice real-time PREFUL (RT-PREFUL) acquisition with compressed sensing and parallel imaging reconstruction to establish a V/Q scan of the whole lung in one minute. The comparison with conventional PREFUL technique showed very similar ventilation results and comparable perfusion results with 9-fold acceleration.

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