Abstract #4099

Free-Breathing Magnetic Resonance Elastography of the Lung: A Repeatability and Reproducibility Study.

Faisal Fakhouri^1,2, Stephan Kannengiesser³, Josef Pfeuffer³, and Arunark Kolipaka^1,2

¹Department of Biomedical Engineering, The Ohio State University, Columbus, OH, United States, ²Department of Radiology, The Ohio State University, Wexner Medical Center, Columbus, OH, United States, ³MR Application Development, Siemens Healthcare GmbH, Erlangen, Germany

Lung stiffness is altered in many diseases making it an important biomarker of understanding lung mechanics. Many patients struggle to hold their breath during scanning due to shortness of breath. We have developed a free-breathing spin-echo-spiral magnetic resonance elastography (MRE) sequence, and a feasibility study was performed on 5 healthy volunteers. It was found that the shear stiffness of the lung during normal breathing was 1.9±0.51kPa and 8.87±1.44kPa with and without considering lung density correction, respectively. Also the measurements were repeatable and reproducible.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.