Abstract #4121

A comparative study of multi-shot diffusion-weighted imaging (DWI) using multiplexed sensitivity encoding (MUSE) and conventional single-shot echo-planar imaging (EPI) DWI in breast cancer

Gabrielle C. Baxter¹, Ramona Woitek¹, Amy J. Frary¹, Gavin C. Houston², Martin J. Graves³, Fiona J. Gilbert¹, and Andrew J. Patterson³

¹Department of Radiology, University of Cambridge, Cambridge, United Kingdom, ²Global Research Organisation, GE Healthcare, Buckinghamshire, United Kingdom, ³Department of Radiology, Addenbrooke's Hospital, Cambridge, United Kingdom

MUSE (multiplexed sensitivity encoding) is a multi-shot echo-planar imaging (EPI) technique used in diffusion-weighted imaging (DWI) that reduces distortion and blurring compared to single-shot EPI. Experiments using a breast phantom aimed to investigate the effect of varying parallel acceleration and number of shots on geometric distortion and quantification of the apparent diffusion coefficient (ADC). A refined protocol was applied to a small cohort of patients to comparatively assess improvements in image quality.

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