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Abstract #4266

18F-Fluoroethyltyrosine PET and Multiple Quantum Filtered Sodium MRI in Cerebral Gliomas

Wieland A. Worthoff1, Aliaksandra Shymanskaya2, Philipp Lohmann1, Karl-Josef Langen1,3,4, and N. Jon Shah1,2,4,5

1Institute of Neuroscience and Medicine - 4, Forschungszentrum Jülich GmbH, Jülich, Germany, 2Institute of Neuroscience and Medicine - 11, Forschungszentrum Jülich GmbH, Jülich, Germany, 3Department of Nuclear Medicine, RWTH Aachen University, Aachen, Germany, 4Jülich-Aachen Research Alliance (JARA) - Section JARA-Brain, Aachen, Germany, 5Department of Neurology, RWTH Aachen University, Aachen, Germany

[18F]-FET-PET and sodium MRI were carried out on a cohort of patients with untreated cerebral gliomas. It is shown that the results from multiple quantum filtered sodium MRI using the enhanced SISTINA sequence are related to IDH mutational status in contrast to [18F]-FET-PET, thus providing the diagnostic potential to predict the genetic profile of gliomas.

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