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Abstract #4336

Performance analysis and optimization of MR-based attenuation correction in hybrid PET/MR

Katharina Schröder1,2,3, Harald H. Quick1,2, and Marcel Gratz1,2

1High Field and Hybrid MR Imaging, University Hospital Essen, Essen, Germany, 2Erwin L. Hahn Institute for MRI, University of Duisburg-Essen, Essen, Germany, 3TU Dortmund, Dortmund, Germany

The recent approach of MR-based attenuation correction in hybrid PET/MR, using a Dixon-VIBE based 4-component µ-map along with an atlas-based bone model, was analysed regarding its accuracy and potentials to reduce deviations from the ground truth. Various CT-based µ-maps were synthesized and the influence of each component on the standardized uptake values was determined for 16 patients. Furthermore, the generated µ-maps were quantitatively compared to the original PET/MR-based µ-maps. It was demonstrated that an adjustment of the lung values and introduction of a second tissue compartment increases the accuracy of the calculated standardized uptake values, particularly for heart and abdomen.

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