Abstract #4397

Diagnostic performance of chemical shift in/opposed phase (IOP) and fat-fraction to evaluate the presence of intra-tumoral fat in HCC

Kritisha Rajlawot¹, Jing Zhou², Churong Lin¹, Sichi Kuang¹, Jingbiao Chen¹, Yao Zhang¹, Hao Yang¹, Ying Deng¹, Bingjun He¹, Diego Hernando³, Jin Wang¹, and Scott B Reeder³

¹Department of Radiology, The third affiliated hospital of Sun Yat-sen University, Guangzhou, China, ²The third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China, ³Departments of Radiology and Medical Physics, University of Wisconsin, Madison, W, University of Wisconsin, Madison, WI, Madison, WI, United States

Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver. Previous studies have showed that the presence of intra-tumoral fat has more favorable prognosis of HCC. We aim to compare the diagnostic accuracy of chemical shift encoded fat-fraction at three different flip angles (FA) 3°, 8° and 9°using IDEAL-IQ, in comparison to chemical shift imaging (IOP) to evaluate intra-tumoral fat in HCC.Our results showed higher positive rates of detection of intra-tumoral fat in HCC with IOP (100%) compared to IDEAL IQ at FA 3° (44.4%), FA 8° (55.6%) and FA 9° (88.9%).

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