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Abstract #4418

Fast and whole-brain T2* mapping using QUTE-EPI at 7T

Seonyeong Shin1, Seong Dae Yun1, and N. Jon Shah1,2,3,4

1Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Juelich, Juelich, Germany, 2Institute of Neuroscience and Medicine 11, INM-11, JARA, Forschungszentrum Juelich, Juelich, Germany, 3JARA - BRAIN - Translational Medicine, Aachen, Germany, 4Department of Neurology, RWTH Aachen University, Aachen, Germany

Quantification of T2* relaxation time is of great interest as knowledge of it can be used for clinical diagnosis or optimisation of MR imaging parameters. A typical approach to quantify T2* is to acquire multi-echo data. Although this approach is effective, it still requires a substantial acquisition time for whole-brain coverage. This work aims to employ quantitative echo-planar imaging (QUTE-EPI) at 7T for fast and whole-brain T2* mapping. The performance of QUTE-EPI was directly compared to that of a conventional multi-echo gradient-echo sequence (MEGE). The estimated T2* values were quantitatively analysed for the regions of grey matter (GM) and white matter (WM).

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