We propose a novel Inversion-Recovery Look-Locker 3D-EPI sequence for rapid T1 mapping. The inherent SNR benefit of a 3D acquisition, segmentation along both phase encode directions and a turbofactor introduced to reduce the number of required inversions can be traded freely for acquisition speed, SNR, resolution and geometric distortions. Aside from quantitative validation, two high-resolution T1 mapping applications are demonstrated at 7T: whole-brain with minimal distortions, and reduced field-of-view with geometric distortions matched to corresponding fMRI data. The results show high T1 accuracy for several turbofactor and flip angle combinations compared to a single-slice inversion-recovery 2D-EPI reference.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords