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Abstract #4488

Free-breathing MRI of the upper abdomen assisted by motion modelling

Robert I Johnstone1,2, David Atkinson3, Manil Chouhan3, Ricky A Sharma4, and Jamie R McClelland1

1Centre for Medical Image Computing, University College London, London, United Kingdom, 2Medical Physics, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom, 3Centre for Medical Imaging, University College London, London, United Kingdom, 4NIHR University College London Hospitals Biomedical Research Centre, University College London, London, United Kingdom

This study demonstrates the use of motion modelling and super resolution reconstruction (SRR) to produce an isotropic 3D image of the upper abdomen during free breathing.

Sagittal and coronal 6 mm 2D slices are acquired throughout the volume of interest. The slices are repeated with sub-voxel offsets to facilitate SRR. An interleaved navigator slice is also acquired.

The navigator slice is processed with non-rigid registration and principal component analysis, to give two motion surrogate signals. These signals are used to control the motion model. The motion model and the SRR are jointly optimised using an iterative scheme.

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