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Abstract #4490

Effects of Image Registration in Dynamic Contrast-Enhanced MRI of the TMJ

Lea Sjurine Starck1,2, Erling Andersen2,3, Ondřej Macíček4, Oskar Angenete5,6, Thomas Augdal7, Erlend Hodneland2,8, Radovan Jiřík4, Karen Rosendahl9,10, and Renate Grüner1,2,7

1Dept. of Physics and Technology, University of Bergen, Bergen, Norway, 2Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Bergen, Norway, 3Dept. of Clinical Engineering, Haukeland University Hospital, Bergen, Norway, 4Institute of Scientific Instruments, Czech Academy of Sciences, Brno, Czech Republic, 5Dept. of Radiology and Nuclear Medicine, St. Olav hospital HF, Trondheim, Norway, 6Dept. of Circulation and Medical Imaging, Norwegian university of Science and Technology, Trondheim, Norway, 7Dept. of Radiology, University Hospital of North Norway, Tromsø, Norway, 8Norse, Bergen, Norway, 9Dept. of Radiology, Haukeland University Hospital, Bergen, Norway, 10Dept. of Clinical Sciences, University of Bergen, Bergen, Norway

The effect of elastic and affine motion correction in dynamic contrast enhanced MRI ofthe temporomandibular joints in children is investigated. Imaging in children is particularly difficultdue to motion. This hampers DCE-MRI and pharmacokinetic estimations for their potentialdiagnostic value in these children with Juvenile Idiopathic Arthritis with possible TMJ involvement.The relative enhancement curves obtained with different motion correction approaches arecompared with the curves calculated with the Gamma Capillary Transit Time model. It is found thatwhen image registration is applied, a greater number of participants can be analysed. The elasticmotion correction approach outperforms the affine approach.

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