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Abstract #4495

MR-assisted PET motion correction improves tumor-to-background and contrast-to-noise ratios in a phantom study with ground truth reference

Sihao Chen1, Cihat Eldeniz1, Richard Laforest1, and Hongyu An1

1Washington University in St. Louis, Saint Louis, MO, United States

Respiratory motion leads to signal blurring and reduced tumor-to-background (TBR) and contrast to noise (CNR) ratios. As a result, it can severely affect the detectability of lesions in PET imaging.1,2 Simultaneous PET/MR imaging uniquely allows for MR assisted motion correction in PET imaging.3 In this study, we have demonstrated that the MR assisted PET motion correction significantly improves both tumor-to-background and contrast-to-noise ratios, leading to better lesion detection.

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