Abstract #4499

Correcting breast MRI with a generic B-1(+) template for T-1 map calculation

Lieke van den Wildenberg¹, Erwin Krikken¹, Jannie P. Wijnen¹, Josien P. W. Pluim², Dennis W. J. Klomp¹, and Michael J. van Rijssel¹

¹Center for Image Sciences, UMC Utrecht, Utrecht, Netherlands, ²Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands

In 7T breast MRI, the use of local transmit coils causes an inhomogeneous B₁⁺ field, decaying towards the pectoral muscle. This leads to differences in image contrast throughout the breasts and in dynamic contrast enhanced (DCE) MR images it has a direct influence on the enhancement kinetic curves. Therefore a correction is necessary. We used B₁⁺ simulations to generate a template to correct the images, because the dynamic range of measured B₁⁺ maps is often insufficient. We validated the template on eleven volunteers. T₁-maps were calculated using the generic template as a first step of correcting the DCE images.

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