Abstract #4561

Combining Parallel Imaging and Model-based Reconstruction for Isotropic 3D T2 mapping with Multi-Echo GRASE

Gian Franco Piredda^1,2,3, Tom Hilbert^1,2,3, Reto Meuli², Josef Pfeuffer⁴, Jean-Philippe Thiran^2,3, and Tobias Kober^1,2,3

¹Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, ²Department of Radiology, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland, ³LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ⁴Application Development, Siemens Healthcare GmbH, Erlangen, Germany

Classical T2 mapping based on 2D multi-echo spin-echo sequences achieves only limited across-slice resolutions. For clinical use, acquisitions with high isotropic resolution are however desirable, resulting in clinically prohibitive scan times. To this end, we propose a 3D multi-echo gradient and spin echo sequence with CAIPIRINHA and an additional model-based acceleration for T2 estimation. The combination of these techniques allows for whole-brain T2 mapping with 1.6mm-isotropic resolution in 3:26 min. The proposed framework was tested both in phantom and in vivo experiments.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.