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Abstract #4567

A novel strategy to perform the dual flip angle method for the fast and accurate T1 mapping by MRI

Steven Yee1, Michael Fadell2, Mark S Brown2, and Seonghwan Yee2

1SUNY Geneseo, Geneseo, NY, United States, 2University of Colorado School of Medicine, Aurora, CO, United States

Fast T1 mapping can be done by utilizing dual flip angles in acquiring spoiled gradient echo signals. However, its accuracy may be questionable even when the suggested optimal flip angle pair is used. Noting that the faithful action of the prescribed flip angles is the key to the accuracy, we present here a novel dual flip angle method by which the system-specific RF-pulse fidelity of flip angles can be validated and, if necessary, calibrated to improve the T1 accuracy in a wide in vivo range. We tested this method on a few 1.5 or 3T MRI systems of major vendors.

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