In previous work, Echo-Planar Imaging (EPI) has been used in combination with a CAIPIRINHA undersampling scheme, as in SMS blipped CAIPI or 3D CAIPI EPI, for highly accelerated BOLD, perfusion and diffusion weighted imaging. In a separate development, Compressed Sensing (CS) was employed in combination with parallel imaging to significantly accelerate a range of non-EPI 3D imaging sequences. In general, this is achieved by using a variable-density randomized sampling scheme which gives aliasing artefacts a noise like appearance. This work explores the use of CS to accelerate 3D EPI acquisitions and demonstrates an improved performance compared to the CAIPIRINHA approach.
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