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Abstract #4602

Metal Artifacts Reduction in DWI using Point Spread Function (PSF) Encoding

Sisi Li1, Yishi Wang1,2, Zhangxuan Hu1, Li Guan3, Yong Hai3, Xiao Han4, Yu Ma5, Hanwen Zhang3, Xiaolong Chen3, and Hua Guo1

1Department of Biomedical Engineering, Center for Biomedical Imaging Research, Beijing, China, 2Philips Healthcare, Beijing, China, Beijing, China, 3Chao Yang Hospital, Beijing, China, 4Beijing Jishuitan Hospital, Beijing, China, 5Tsinghua University Yu Quan Hospital, Beijing, China

Though metal artifacts have been well-resolved in anatomical imaging by three dimensional multispectral imaging (3D-MSI) methods, diffusion weighted imaging (DWI) near metallic implants still remains a challenge, impeding various clinical applications. Point-Spread-Function encoded EPI (PSF-EPI) combined with Tilted-CAIPI can achieve highly accelerated distortion- and blurring-free high resolution DWI. By using an additional phase encoding, artifacts induced by severe susceptibility inhomogeneity around metal can be reduced even under a high acceleration rate. The reliable performance of PSF-EPI technique in metal artifacts reduction in DWI is demonstrated on phantom, in vitro swine forearm and in vivo patients.

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