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Abstract #4750

Rapid, Free-Breathing, Cine MRI for Patients with a Cardiac Implantable Electronic Device: A Preliminary Study

KyungPyo Hong1, Jeremy D Collins1,2, Daniel C Lee1,3, and Daniel Kim1,4

1Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States, 2Radiology, Mayo Clinic, Rochester, MN, United States, 3Cardiology, Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States, 4Biomedical Engineering, Northwestern University, Evanston, IL, United States

Standard ECG-gated, breath-held cardiac cine MRI often produces poor image quality in patients with a cardiac implantable electronic device (CIED) due to off-resonance effects, high prevalence of arrhythmia, and/or difficulty in breath-holding. This study seeks to develop a 16-fold accelerated, free-breathing cine MRI pulse sequence using a combination of a gradient echo readout, compressed sensing, and optimal Cartesian k-space sampling. The results from this study shows that an optimal k-space sampling scheme produces superior results compared to random and Poisson disc k-space sampling patterns in imaging phantoms and patients.

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