Abstract #4842

A Realistic Numerical Simulation for Fetal Cardiac MRI

Christopher W. Roy^1,2,3, Davide Marini⁴, William P Segars⁵, Mike Seed^4,6, and Christopher K. Macgowan^2,3

¹Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ²Medical Biophysics, University of Toronto, Toronto, ON, Canada, ³Translational Medicine, The Hospital for Sick Children, Toronto, ON, Canada, ⁴Pediatric Cardiology, The Hospital for Sick Children, Toronto, ON, Canada, ⁵Radiology, Duke University Medical Center, Durham, NC, United States, ⁶Pediatrics and Diagnostic Imaging, University of Toronto, Toronto, ON, Canada

Validating new techniques for fetal CMR is challenging due to random fetal movement that precludes repeat measurements. Consequently, fetal CMR development has been largely performed using physical phantoms or postnatal volunteers. In this work, we present an open-source simulation designed to aide in the development and validation of new approaches for fetal CMR. Our phantom: Fetal XCMR, builds on established methods for simulating MR acquisitions but is tailored toward the dynamic physiology of the fetal heart and body. We present comparisons between the Fetal XCMR phantom and data acquired in utero, resulting in image quality, anatomy, tissue signals and contrast.

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