Abstract #4965

Optimal Strategies for CSF and Tissue Suppression in Velocity-Selective Arterial Spin Labeling

Mu-Lan Jen¹, James H Holmes², and Kevin M Johnson^1,3

¹Department of Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, ²University of Wisconsin-Madison, Madison, WI, United States, ³Department of Radiology, University of Wisconsin - Madison, Madison, WI, United States

Velocity-selective arterial spin labeling (VS-ASL) inherently suffers from low signal-to-noise ratio (SNR) and contamination from cerebrospinal fluid (CSF) motion. This study aims to develop and evaluate optimal strategies for inversion based background suppression (BGS). Specifically, we investigate the influence of the timing of signal nulling and inflow from outside the region of interest. Our results suggest an optimized BGS which allows VS-ASL based measurement of cerebral blood flow maps with reduced CSF contamination while preserving sufficient perfusion signal.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.