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Abstract #4983

Calculation of molar relaxivity and concentration map of Gd-DTPA map using quantitative parameter map before and after injection for brain metastasis

Yuki Matsumoto1, Masafumi Harada1, Yuki Kanazawa1, Takashi Abe1, Maki Otomo1, Yo Taniguchi2, Masaharu Ono3, and Yoshitaka Bito3

1Tokushima University, Tokushima, Japan, 2Research & Development Group, Hitachi, Ltd., Tokyo, Japan, 3Healthcare Business Unit, Hitachi, Ltd., Tokyo, Japan

R1 map and susceptibility maps before and after injection of Gd-DTPA were calculated using quantitative parameter map technique. Then, concentration map (CM) of the Gd-DTPA was calculated using the susceptibility maps. A linear regression between CM and R1post - R1pre map was performed. The comparison between the CM and R1pre-R1post map each of the metastasis demonstrated a strong correlation (y = 4.0966 - 0.46535, R=0.95) and relaxivity map r1 was empirically calculated from the linear regression. A slope of the linear regression means the relaxivity in metastasis and it approximately matched the relaxivity of the Gd-DTPA in plasma at 3T.

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