Abstract #4983

Calculation of molar relaxivity and concentration map of Gd-DTPA map using quantitative parameter map before and after injection for brain metastasis

Yuki Matsumoto¹, Masafumi Harada¹, Yuki Kanazawa¹, Takashi Abe¹, Maki Otomo¹, Yo Taniguchi², Masaharu Ono³, and Yoshitaka Bito³

¹Tokushima University, Tokushima, Japan, ²Research & Development Group, Hitachi, Ltd., Tokyo, Japan, ³Healthcare Business Unit, Hitachi, Ltd., Tokyo, Japan

R1 map and susceptibility maps before and after injection of Gd-DTPA were calculated using quantitative parameter map technique. Then, concentration map (CM) of the Gd-DTPA was calculated using the susceptibility maps. A linear regression between CM and R1post - R1pre map was performed. The comparison between the CM and R1pre-R1post map each of the metastasis demonstrated a strong correlation (y = 4.0966 - 0.46535, R=0.95) and relaxivity map r1 was empirically calculated from the linear regression. A slope of the linear regression means the relaxivity in metastasis and it approximately matched the relaxivity of the Gd-DTPA in plasma at 3T.

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