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Abstract #5044

Multiple TR Approach for Direct Detection of Fast Oscillating Magnetic Fields

Je-Seok Ham1, Hyun-Soo Lee1, and Sung-Hong Park1

1Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea, Republic of

Due to weak amplitude and fast oscillation, it is still controversial whether neuronal activities can be directly detected through MR imaging. In this study, we propose a novel method, multiple‑TR approach, which utilized 1) multi-phase acquisition and 2) frequency spectrum multiplication for detecting weak and fast oscillating magnetic fields. We demonstrated with phantom experiments that SNR at the stimulation frequency on the spectrum was remarkably enhanced with the higher number of TRs under almost the same scan time, amplifying oscillation frequency component while suppressing systematic noises. This proposed approach will increase possibility of directly detecting neural oscillations in vivo.

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