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Abstract #5047

Discrete Laplacian Estimation Using Projection onto ROtating Median Sets (PROMS) for MR Electrical Property Tomography

Han-Jae Chung1,2,3, Jong-Min Kim1,2,3, You-Jin Jeong1,2,3, Jae-Won Yoo1,2,3, Jeong-Hee Kim2,4, Chulhyun Lee5, and Chang-Hyun Oh1,2,3,6

1Electronics and Information Engineering, Korea University, Seoul, Korea, Republic of, 2Korea Artificial Organ Center, Korea University, Seoul, Korea, Republic of, 3ICT Convergence Technology for Health and Safety, Korea University, Sejong, Korea, Republic of, 4Research Institute for Advanced Industrial Technology, Korea University, Sejong, Korea, Republic of, 5Korea Basic Science Institute, Cheongju, Chungbuk, Korea, Republic of, 6Corresponding author,, Korea, Republic of

The novel contrast mechanism, MREPT, is still difficult to use in the clinical field. This is because the reconstruction of MREPT is performed under many assumptions, which lead to limitations for solving the governing equations, and is highly noise sensitive characteristics to noise in practical use. In this work, we propose a new discrete Laplacian estimation method using Median kernel sets, which has fast and noise-robust features, and show its performance by using in-vivo experiments and EM simulation. For validation of the proposed method, three healthy volunteers were scanned on a clinical MRI system with identical imaging parameters.

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