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Abstract #5057

Investigating the Relationship Between Conductivity and Bound Sodium Fractions at 21.1 T

Ghoncheh Amouzandeh1,2, Nastaren Abad2,3, Jens T Rosenberg2, and Samuel C Grant2,3

1Physics, Florida State University, Tallahassee, FL, United States, 2National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL, United States, 3Biomedical Engineering, Florida State University, Tallahassee, FL, United States

This study investigates the relation between electrical conductivity evaluated using MR Electrical Properties Tomography (EPT), sodium concentrations and their mobility. In particular, the project seeks to determine if conductivity values calculated from EPT differentiate between bound and free sodium measured by triple quantum (TQ) coherence selection. TQ and EPT acquisitions were evaluated over a range of sodium concentration and with different binding conditions to provide insight into the sources of tissue conductivity changes. The correlation between electrical conductivity and ionic content can provide more in depth understanding of how sodium ions are changing in pathological conditions.

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