In order to visualize the concentration and distribution of magnetic nanoparticles in pre-clinical research of magnetic nanoparticles-based sentinel lymph node biopsy, Quantitative Susceptibility Mapping(QSM) is a promising quantification tool in MRI. However, the strong magnetic field generated by high concentrations of magnetic particles causes the failure of conventional B0 map used in QSM. A novel spin echo-based View Line sequence with radius basic function interpolation-based reconstruction method has been proposed to obtain the B0 map for high concentrations of magnetic nanoparticles. This method has been verified by MRI data and simulation data for a range of iron in Resovist from 41 ug to 654 ug. Comparison of the reconstructed field map and theoretical field map provides normalized root mean square of $$$0.085\pm 0.054$$$ for the line field map, and $$$0.065 \pm 0.024$$$ for the interpolated field map.
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