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Abstract #5067

B0 Field Map estimation with View Line sequence

Shuang Liu1, Wenqi Qiu1, Gabriel Della Maggiora2, Akihiro Kuwahata1, Moriaki Kusakabe3, Pablo Irarrazaval2, and Masaki Sekino1

1Electrical Engineering Graduate School of Engineering, The University of Tokyo, Tokyo, Japan, 2Department of Electronic & Electrical Engineering, Pontifical Catholic University of Chile, Santiago, Chile, 3Faculty and Graduate School of Agriculture and Life Science, The University of Tokyo, Tokyo, Japan

In order to visualize the concentration and distribution of magnetic nanoparticles in pre-clinical research of magnetic nanoparticles-based sentinel lymph node biopsy, Quantitative Susceptibility Mapping(QSM) is a promising quantification tool in MRI. However, the strong magnetic field generated by high concentrations of magnetic particles causes the failure of conventional B0 map used in QSM. A novel spin echo-based View Line sequence with radius basic function interpolation-based reconstruction method has been proposed to obtain the B0 map for high concentrations of magnetic nanoparticles. This method has been verified by MRI data and simulation data for a range of iron in Resovist from 41 ug to 654 ug. Comparison of the reconstructed field map and theoretical field map provides normalized root mean square of $$$0.085\pm 0.054$$$ for the line field map, and $$$0.065 \pm 0.024$$$ for the interpolated field map.

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