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Abstract #0005

Multiphoton Magnetic Resonance Imaging

Victor Han1 and Chunlei Liu1,2
1Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, United States, 2Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, United States

We present a fully geometric view of multiphoton excitation by taking a particular rotating frame transformation. In this rotating frame, we find that multiphoton excitations appear just like single-photon excitations again, and thus, we can readily generalize concepts already explored in standard single-photon excitation. With a homebuilt low-frequency (~ kHz) coil, we execute a standard slice-selective pulse sequence with all of its excitations replaced by their equivalent two-photon versions. With a multiphoton interpretation of oscillating gradients, we present a novel way to transform a standard slice-selective adiabatic pulse into a multiband one without modifying the RF pulse shape itself.

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