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Abstract #0029

Retrospective Vessel Selective Perfusion Imaging with Displacement Spectrum Imaging (DiSpect) at Multiple Mixing Times

Ekin Karasan1, Michael Lustig1, and Zhiyong Zhang1,2
1Department of Electrical Engineering, University of California, Berkeley, CA, United States, 2Institute for Medical Imaging Technology, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China

Displacement spectrum imaging (DiSpect) performs multiple scans with increasing displacement (DENSE) encodings. It can resolve the multi-dimensional spectrum of displacements that spins exhibit over the mixing time between tagging and imaging. This work presents two innovations: 1) Imaging dynamic displacement spectra by repeatedly imaging after tagging, each image corresponding to an increased mixing time. 2) Post acquisition, it is possible to retrospectively select source vessels from the displacement maps and display only their contribution to perfusion in the imaging slice. We demonstrate feasibility in flow phantom and in-vivo brain at 3T.

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