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Abstract #0049

Quantitative Myelin Mapping in Human Brain Using a Short TR Adiabatic Inversion Recovery Prepared Ultrashort Echo Time (STAIR-UTE) Sequence

Yajun Ma1, Hyungseok Jang1, Zhao Wei1, Zhenyu Cai1, Yanping Xue1, Eric Y Chang2, Jody Corey-Bloom1, and Jiang Du1
1UC San Diego, San Diego, CA, United States, 2VA health system, San Diego, CA, United States

To quantitatively image myelin on clinical scanners, we propose a Short TR Adiabatic Inversion Recovery prepared UTE (STAIR-UTE) sequence for in vivo brain imaging. With STAIR technique, long T2 tissues with a broad range of T1s can be sufficiently suppressed. Healthy volunteer has a higher myelin proton density in white matter than that in patient with multiple sclerosis.

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