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Abstract #0072

Semi-Automated Whole Body Neonatal Regional Fat Quantification Using Dixon Chemical Shift (CSI) MRI at 3.0 Tesla

Jonathan P Dyke1, Kevin Oh1, Amanda Garfinkel2, Alan M Groves3, and Arzu Kovanlikaya1
1Radiology, Weill Cornell Medicine, New York, NY, United States, 2Pediatrics, Weill Cornell Medicine, New York, NY, United States, 3Pediatrics, Mount Sinai School of Medicine, New York, NY, United States

Whole body fat fraction was previously published by our group in term and preterm infants using Dixon CSI MRI. Advanced semi-automated regional fat quantification was performed yielding: subcutaneous adipose tissue(SAT), visceral adipose tissue(VAT), brown adipose tissue (BAT) volumes and hepatic fat fraction (HFF). Whole body VAT volume (cc) was increased in preterm infants (3.4%±1.5%) compared to term (2.4%±0.9%) (p=0.079) when normalized to total body volume (cc). HFF and BAT did not differ between term and preterm infants (p>0.25). CSI MRI allows quantification of regional fat depots in preterm infants which may potentially help optimize nutritional management and monitor growth.

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