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Abstract #0102

Dynamic PRF and T1-based 3D Thermometry in the Liver using a Variable Flip Angle Stack-of-Radial Technique

Le Zhang1, Tess Armstrong1,2, and Holden H. Wu1,2,3
1Radiological Sciences, University of California, Los Angeles, Los Angeles, CA, United States, 2Physics and Biology in Medicine, University of California, Los Angeles, Los Angeles, CA, United States, 3Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States

MR thermometry in the liver is challenged by mismatch between baseline and dynamic images caused by motion, leading to temperature errors. To address motion, previous methods had to compromise spatial coverage to increase temporal resolution. We propose a variable-flip-angle (VFA) 3D stack-of-radial technique for combined proton resonance frequency shift (PRF) and T1-based MR thermometry with volumetric coverage and high spatiotemporal resolution. Accurate VFA T1 calculation is achieved by synthesizing B1+ maps that match the liver position in dynamic images. A multi-baseline approach is used for accurate dynamic PRF measurements. Results from non-heating scans demonstrate reliable liver T1 and PRF measurements.

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